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The source file '/VIDEO_TS/VTS_05_1.VOB' is corrupt or invalid at offset 65038336, attempting to work around
The source file '/VIDEO_TS/VTS_05_1.VOB' is corrupt or invalid at offset 65040384, attempting to work around
The source file '/VIDEO_TS/VTS_05_1.VOB' is corrupt or invalid at offset 65042432, attempting to work around
DEBUG: Code 149 at zH6S?E5K85!+n7Kw98h:29399243
DEBUG: Code 0 at vKB(dGEhkkgO}MEm^zu\*:29398645
DEBUG: Code 0 at vKB(dGEhkkgO}MEm^zu\*:29398645
DEBUG: Code 0 at %|FJPa;?C'J)_V:>o:121263728
DEBUG: Code 0 at %|FJPa;?C'J)_V:>o:121263176
DEBUG: Code 0 at %|FJPa;?C'J)_V:>o:29393930
DEBUG: Code 0 at vKB(dGEhkkgO}MEm^zu\*:29399013
LIBMKV_TRACE: Exception: Error while reading input
Failed to save title 0 to file C:/Users/Public/Videos/Feature Films/TRANSFORMERS/title00.mkv
0 titles saved, 1 failed

Several of the disks you're having problems with have been successfully ripped by others. And at least a couple of them are generating "corrupt or invalid" messages at the same general area of the disk.

When was the last time you cleaned the drive?

Mike will want the full debugging log for each disk, not just "the highlights" you've posted.

From all your logs it seems that you're trying to open some badly-ripped discs. If it is not the case, a workaround can be added, but you need to send the full log files to support@makemkv.com . By a full log file I mean the log file created by MakeMKV, its file name is shown at start. The full log file will have additional information.