www.makemkv.com

Debug log started at Sun Dec 18 02:38:30 2016 , written by MakeMKV v1.10.3 win(x64-release)
Using 524544KB for read cache.
001005:0000 MakeMKV v1.10.3 win(x64-release) started
001004:0000 Debug logging enabled, log will be saved as C:\Users\Hans Luke/MakeMKV_log.txt
003007:0000 Using direct disc access mode
003002:0000 Calculated BUP offset for VTS #0 does not match one in IFO header.
003002:0000 Calculated BUP offset for VTS #1 does not match one in IFO header.
003008:0000 Titleset start sector mismatch for titleset 1 : 51 != 144
Title skip vts=1 pgcn=1 hash=E6B20360D69AD99E
005010:0000 Failed to open disc
003007:0000 Using direct disc access mode
003002:0000 Calculated BUP offset for VTS #0 does not match one in IFO header.
003002:0000 Calculated BUP offset for VTS #1 does not match one in IFO header.
003008:0000 Titleset start sector mismatch for titleset 1 : 51 != 144
Title skip vts=1 pgcn=1 hash=E6B20360D69AD99E
005010:0000 Failed to open disc
Application exited at Sun Dec 18 02:41:22 2016

"Movie located in a folder" ... does this mean you've already ripped the movie to disk, and you're using MakeMKV to process that copy?

The log indicates that the DVD file structure is damaged.

Yes, this was a movie copied in about 2008. We have been watching it until Windows 10 stopped playing it, so, as with others, we want to make a readable copy.

OK, then there are additional questions.

Is it a DVD ISO file? If so, are you having MakeMKV open that file, or are you using some method to mount the ISO as a "drive" in Windows?

Is it a "DVD file structure", i.e., rather than being a copy of the complete DVD in one large file, it is just the VOB and other files from the disk?

It is not an .iso file. It is
VIDEO_TS\VIDEO_TS.BUP"
VIDEO_TS\VIDEO_TS.IFO"
VIDEO_TS\VIDEO_TS.VOB"
VIDEO_TS\VTS_01_0.BUP"
VIDEO_TS\VTS_01_0.IFO"
VIDEO_TS\VTS_01_1.VOB"
VIDEO_TS\VTS_01_2.VOB"
VIDEO_TS\VTS_01_3.VOB"
VIDEO_TS\VTS_01_4.VOB"
VIDEO_TS\VTS_01_5.VOB"