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I tried putting Happy Feet through MakeMKV and it gave me the following error:

Saving 1 titles into directory /Volumes/Seagate Backup Plus Drive/Movies
Drive DVD+R-DL OPTIARC DVD RW AD-5670SC 4BH2 has RPC protection that can not be bypassed. Change drive region or update drive firmware from http://tdb.rpc1.org. Errors likely to follow.
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Error 'Scsi error - ILLEGAL REQUEST:READ OF SCRAMBLED SECTOR WITHOUT AUTHENTICATION' occurred while reading '/VIDEO_TS/VTS_01_1.VOB' at offset '2048'
Failed to save title 0 to file /Volumes/Seagate Backup Plus Drive/Movies/HAPPY_FEET_t00.mkv
0 titles saved, 1 failed

What's wrong? I don't understand what it's trying to tell me.

It is very rare to see the "has RPC protection that can not be bypassed" message, because usually MakeMKV can work around it.

Have you recently ripped a disk that was "out of region" for you?

No I have not.