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Open MakeMKV, go to Preferences->General, and change your MakeMKV directory to something a user can write to. I use c:\makemkvsvq myself, but it is important that the directory NOT be the installation directory. That directory can only be written to by an administrator. MakeMKV is trying to save da...

Here are the error codes that are displayed for the 2 discs in question

I am backing up my UHD BD copy of Game of Thrones S01, I was able to back up the first 2 discs without issue, however, MakeMKV is unable to open the last 2 discs.

Has anybody else run into this issue?